https://evergrenlab.com/news daily 0.75 2023-09-13 https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/8d7c08e6-9526-4bde-acf3-bf2711d7b654/James+Emma.jpg https://evergrenlab.com/news/get-out-there-xcz6a monthly 0.5 2021-03-31 https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/1617188821597-CZ0WNK6D0JB2BNMD3KKV/ELOVL5.jpg News - New publication https://evergrenlab.com/home daily 1.0 2025-01-13 https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/1616586716633-UTI9RUKP3J1Q28NROFB2/cell+cover+small.jpg Home - Our research mission We are a cell biology lab that is interested in understanding fundamental membrane trafficking mechanisms and how they may contribute to driving cancer progression. Our research focuses on investigating the molecular mechanisms that underpins trafficking of membrane vesicles from the plasma membrane and intracellular organelles and also how membrane-binding proteins can shape and cut membranes with high spatial and temporal precision. These pathways are critical for regulating cell signalling by receptors at the cell surface, internalisation of nutrients, energy homeostasis, stress response, cell viability and proliferation. https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/1616586016512-WRDMMIKY499CF0TVTF76/Figure+1.png Home - Our Tool Box Protein biochemistry - to map novel protein-protein interactions. Light and electron microscopy to analyse protein localisation and changes in morphology due to gene knockdowns or protein overexpression. Co-culture systems to study EphB2-ephrinB1 cell repulsion. Analysis of ex vivo culture of patient derived tissue explants in collaboration with Prof. Lisa Butler (University of Adelaide). https://evergrenlab.com/projects daily 0.75 2021-11-11 https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/40442427-0cd3-428a-83ea-d9b4e55b2b9d/graphical+abstract.png Projects - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/1617187998220-MTP2LFEDE5HJY5OJ5AMX/ER%2BLD.jpg Projects https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/1617187546390-WUA25KVMZ45SODU9MUJU/ER+swirl.jpg Projects https://evergrenlab.com/partners daily 0.75 2024-07-22 https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/ed1b9c22-c97c-4e31-8d61-8202c337ba01/graphical+abstract.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/beaa26f6-1c77-4e51-91c9-e6e48b12542c/cell+cover+small_Proxy.png Publications - Make it stand out The paper was highlighted in Cell by Jim Hurley - “Friction at the BAR leads to membrane breakup”. https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/08cfbf30-ab95-4008-bc6e-7f5ae173764d/Eps15R+graphical+abstract.jpg Publications Evergren, E.*, Cobbe, N. and McMahon, H. T. (2017). Eps15R and clathrin regulate EphB2-mediated cell repulsion. Traffic 17, 240. https://doi.org/10.1111/tra.12531 *corresponding author https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/0b608759-6d44-400c-a978-3eb66b00f9ed/ELOVL5.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/30e44a43-d3ac-4b25-8ecb-deb44132689c/Copy+of+Golgi+vesicle+trafficking.png Publications - CaMKK2 is involved in maintaining various physiological and cellular processes within the cell that regulate energy homeostasis and cell growth. Consequently, its deregulation has a role in multiple human metabolic diseases including obesity and cancer. Here, we review recent insights into the role of CaMKK2 in membrane trafficking mechanisms and discuss the functional implications . https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/d09a9187-d0ed-4241-b978-7aff4c1356ce/Itch+schem+2.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://evergrenlab.com/team-2 daily 0.75 2025-01-13 https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/1617185067623-LK94VP3326ZL9WZN74FY/IMG_1338.jpg Our Team https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/33ac7d75-8c8c-4261-b981-5d28f6d66002/IMG_6333+copy.png Our Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://evergrenlab.com/take-action daily 0.75 2023-07-19 https://evergrenlab.com/students daily 0.75 2025-05-05 https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/78c4b16a-163c-4856-9c0f-dc9d81e46cf7/Organelle+contact+sites.png https://evergrenlab.com/phd-studentship daily 0.75 2025-09-22 https://images.squarespace-cdn.com/content/v1/5ff4a719c6eb3c3de1ae765d/dccd057d-4e43-4300-b61c-edadd1b59264/MERCS+image+shACSL3.png